MedTrace Logo

Diode Laser and S100A8 in Peri-Implantitis

NCT07524153 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 39

Last updated 2026-04-13

No results posted yet for this study

Summary

Purpose: The aim of this study was to compare the effectiveness of diode laser and combined treatment protocols, applied in addition to mechanical debridement, in the treatment of peri-implantitis on clinical periodontal parameters and S100A8 levels in peri-implant sulcus fluid (PISF).

Methods: A total of 39 patients diagnosed with peri-implantitis were divided into three groups based on the treatment protocols used: Mechanical Debridement, Diode Laser, and Combined Treatment. Probing depth, clinical attachment level, modified plaque index, gingival index, and PISF volume measurements were recorded at baseline and at weeks 4 and 12. S100A8 levels in PISF samples were measured by ELISA.

Conditions

  • Periimplant Diseases
  • S100A8
  • Biomarkers
  • Calprotectin

Sponsors & Collaborators

  • Kırıkkale University

    lead OTHER

Principal Investigators

  • Akif Nalbant, Specialist in Periodontology · Kirikkale University Faculty of Dentistry

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2025-06-01
Completion
2025-10-10

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07524153 on ClinicalTrials.gov