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Hydrolyzed Collagen As A Host Modulation Agent in Non-Surgical Periodontal Treatment

NCT07683741 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-07-06

No results posted yet for this study

Summary

This study was planned on the basis of the hypothesis that 'food supplements containing collagen will support the clinical effectiveness of non-surgical periodontal therapy'. In this context, the aim of the study is to investigate the therapeutic efficacy of collagen-containing food supplement as a host modulation agent in the non-surgical periodontal treatment of individuals with stage 3-4 periodontitis in a clinical and biochemical manner in a comprehensive manner.

Initial day: Anamnesis, diagnosis and index measurements 2 days later, collection of serum samples from the patient, oral hygiene training and straightening of the whole mouth root surface and cleaning of the whole mouth tooth surface The next day, full mouth scalling and root planing are closed with the second session and tablets are started.

End of 2nd month:

Periodontal index measurement and oral hygiene training Collecting serum and tissue samples 2 days later

End of 6th month Periodontal index measurement and oral hygiene training Collecting serum and tissue samples 2 days later

Conditions

  • Periodontitis (Stage 3)

Interventions

DIETARY_SUPPLEMENT

Collagen hydrolyzed peptides

Collagen supplements will not be given in the placebo group.

OTHER

Placebo + cognitive behavioral therapy

placebo will be given.

Sponsors & Collaborators

  • Hatice Yemenoglu

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-10
Primary Completion
2026-05-30
Completion
2026-05-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07683741 on ClinicalTrials.gov