Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.
NCT07680400 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160
Last updated 2026-07-30
Summary
Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents. In surgeries requiring nasotracheal intubation, such as dental and maxillofacial procedures, achieving optimal intubation conditions while minimizing pharmacological exposure is of considerable importance. The combination of propofol and sevoflurane is frequently preferred in pediatric anesthesia because it provides rapid induction and stable hemodynamic conditions. Therefore, this randomized controlled trial aims to evaluate nasotracheal intubation conditions following propofol-sevoflurane induction with reduced pharmacological exposure in pediatric patients. The study is expected to contribute to clinical practice by enhancing patient safety while reducing anesthetic drug use.
Conditions
- Intubating Conditions
Interventions
- DRUG
-
reduced pharmacologic exposure
patients in group R will undergo combination of sevoflurane and propofol only anesthesia induction
- DRUG
-
conventional anesthetic induction
in group C, conventional anesthetic regimen will be used for anesthesia induction
Sponsors & Collaborators
-
Bezmialem Vakif University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 1 Year
- Max Age
- 10 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-07-10
- Primary Completion
- 2026-07-29
- Completion
- 2026-07-29
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Two Different Preparations of Sevoflurane in Induction
NCT01792063 ·Status: COMPLETED ·Phase: PHASE4
-
Target-controlled Infusion of Propofol for Induction of Pediatric Anesthesia
NCT01411020 ·Status: COMPLETED ·Phase: PHASE4
-
Propofol Versus Sevoflurane for Induction of GA in Infants
NCT05105022 ·Status: UNKNOWN ·Phase: NA
-
Efficacy of Propofol-Ketamine and Sevoflurane in Children Undergoing Magnetic Resonance Imaging
NCT06832683 ·Status: COMPLETED ·Phase: NA
-
Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction
NCT01084031 ·Status: COMPLETED ·Phase: NA
-
Genetic Differences in Propofol Pharmacodynamics in Children
NCT04164264 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Intravenous Cannulation In Children During Sevoflurane Induction
NCT03851692 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study to Investigate Plasma Bupivacaine Concentrations in Children Receiving Total Intravenous Anaesthesia and Caudal Analgesia
NCT01216007 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
NCT04527757 ·Status: COMPLETED
-
Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia
NCT06584461 ·Status: COMPLETED ·Phase: PHASE4
-
Remifentanil Use in Pediatric Rigid Bronchoscopy
NCT01947114 ·Status: COMPLETED ·Phase: PHASE4
-
Pre-emptive Local Anesthesia and Sevoflurane Consumption in Pediatric Dental Anesthesia
NCT07608900 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
NCT01150838 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
NCT05769842 ·Status: COMPLETED ·Phase: NA
-
Sevoflurane Versus Propofol for Intubation in Neonatal Intensive Care
NCT01006668 ·Status: UNKNOWN ·Phase: PHASE3
-
Propofol vs. Nasal Dexmedetomidine in Pediatric Agitation and Delirium
NCT06466915 ·Status: COMPLETED ·Phase: PHASE4
-
Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients
NCT05837936 ·Status: RECRUITING
-
Sevoflurane Induced Emergence Agitation
NCT02022488 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of a Modified Propofol Preparation on Injection Pain During Induction of Anesthesia in Children
NCT00287560 ·Status: COMPLETED ·Phase: PHASE3
-
Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery
NCT07410078 ·Status: RECRUITING ·Phase: NA
-
Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation
NCT02284204 ·Status: COMPLETED ·Phase: PHASE2
-
Randomized Study of Propofol Versus Fentanyl and Midazolam in Pediatric Patients Requiring Mechanical Ventilation and Sedation Therapy
NCT00004424 ·Status: COMPLETED ·Phase: NA
-
Induction of Anesthesia With Sevoflurane Preserving Spontaneous Breathing: Cardiorespiratory Effects.
NCT04802122 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia
NCT04310748 ·Status: COMPLETED ·Phase: NA
-
Magnesium Sulfate Versus Other Anesthesia Drugs to Reduce Agitation After Adenotonsillectomy in Pediatric Patients
NCT07433231 ·Status: COMPLETED ·Phase: NA