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Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial

NCT04527757 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2022-03-02

No results posted yet for this study

Summary

Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.

In the paediatric patients, apart from intravenous induction, it is also possible to use in the specific situations inhalation anaesthesia induction with sevoflurane (in the mixture with O2 + air, or O2 + N2O) and secure the i.v. line afterwards in the inhalation anaesthesia. This method is in the paediatric population currently preferred, mainly because of possible fear of the painful venipuncture.

Inhalation anaesthesia induction is possible only in patients without the risk of aspiration/regurgitation of stomach content and in patients without predicted difficult airway. Even if sedative premedication is used, during the inhalation induction excitation stage of the general anaesthesia variably appears, during which hemodynamic sympathoadrenal response and involuntary limbs movement might occur. When deepening inhalation anaesthesia, progression to surgical stage and automatic breathing onset appears. This subsequently facilitates to secure the venous access, without which is is not possible to secure the airway (in exception of the emergency situations - resuscitation).

Conditions

  • Anaesthesia Induction

Interventions

PROCEDURE

Inhalation induction

For the inhalation induction sevoflurane will be used (in the mixture with O2 + air, or O2 + N2O).

PROCEDURE

Intravenous induction

For the intravenous induction, commonly used induction anaesthetics will be used (propofol, etomidate, ketamine, midazolam).

Sponsors & Collaborators

  • Brno University Hospital

    lead OTHER

Principal Investigators

  • Petr Štourač, prof. MD., Ph.D. · Faculty of medicince Masaryk University and University Hospital Brno

Eligibility

Min Age
28 Days
Max Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2022-02-28
Completion
2022-02-28

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04527757 on ClinicalTrials.gov