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Impact of Intracanal Cryotherapy and Corticosteroids on Post Endodontic Pain

NCT07676396 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-06-30

No results posted yet for this study

Summary

The aim of the study: is to evaluate efficiency of using either intracanal corticosteroids or intracanal cryotherapy as a final flush irrigation on post endodontic pain in lower molar teeth with symptomatic irreversible pulpitis. The materials and methods: In this study forty patients with symptomatic irreversible pulpitis in lower molar teeth with pain level of 4 or higher on the visual analogue scale (VAS) will be selected.

Conditions

  • Symptomatic Irreversible Pulpitis (SIP)

Interventions

DRUG

dexamethasone

intra root canal final flush of 5ml of 4mg/ml dexamethasone before obturation

OTHER

Cold Saline

intra root canal final flush of 20ml of cold saline before obturation

OTHER

cold sodium hypochlorite

intra root canal final flush of 20ml of cold sodium hypochlorite before obturation

Sponsors & Collaborators

  • October 6 University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2026-03-01
Completion
2026-03-01

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07676396 on ClinicalTrials.gov