Health Ahead Comparative Effectiveness Study

Summary

The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening - each isolated as a single variable against current practice - on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, allowing results to accumulate on a consistent yardstick across the life of the platform.

The first comparison evaluates static versus interactive personalized health report delivery. Subsequent pre-planned comparisons, added by protocol amendment, evaluate mobile community versus fixed laboratory screening; and a hybrid medical-droid plus human-delivery model versus human-only screening. All participants are simultaneously enrolled in the 100-Year Human Aging Study and the Human Observatory Study, contributing individual longitudinal and population-level causal inference data through those protocols.

Conditions

• Health Services Accessibility
• Rural Health
• Medically Underserved Area
• Preventive Health Services
• Patient Participation
• Health Behavior
• Aging
• Cardiovascular Diseases
• Metabolic Syndrome
• Cognitive Dysfunction
• Frailty
• Activities of Daily Living
• Health Related Quality of Life
• Health Equity
• Telemedecine

Interventions

BEHAVIORAL

Interactive Personalized Health Report

Static versus interactive health report

BEHAVIORAL

Mobile Community-Based Health Screenings

Mobile versus Fixed Laboratory Health Screenings

BEHAVIORAL

Hybrid Medical Droid and Human Delivered Health Screenings

Hybrid Medical Droid and Human Delivered versus Human-Only Delivered Health Screenings

Sponsors & Collaborators

• William Brandenburg, MD

  lead INDUSTRY

Principal Investigators

• William Brandenburg, MD · Longevity Metrics

Study Design

Allocation

NON_RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2026-06-09

Primary Completion

2099-12-31

Completion

2099-12-31

Countries

• United States

Study Locations