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Brief Bronchial Suction for Lung Collapse During Uniportal VATS

NCT07660588 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-06-22

No results posted yet for this study

Summary

The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery (UVATS). This type of surgery is performed through a small incision in the chest, and good lung collapse helps the surgeon see and work safely. The main questions it aims to answer are

1. Does brief bronchial suction improve the quality of lung collapse 1 minute after chest cavity is opened?
2. Does brief bronchial suction help reach satisfactory lung collapse faster?

Researchers will compare patients who receive brief bronchial suction and those who do not. This is to see if suction improves and fastens lung collapse, reduce the need for additional steps if lung is not adequately collapsed, affect inflammation, oxygenation, postoperative pulmonary complications, operative time, and the duration of one-lung ventilation. Participants will

1. Undergo UVATS under general anesthesia
2. Have a double-lumen breathing tube placed as part of the standard anesthetic care
3. Be randomly assigned to either receive bronchial suction for one minute or receive no bronchial suction
4. Have the surgical team assess the quality of lung collapse at different time points
5. Have blood samples taken for interleukin-6, a marker related to inflammation, once during and once after surgery. These samples are collected through a small tube in a vein that is placed as a standard anesthetic care while the participant is under general anesthesia. No extra puncture is required for blood collection.
6. Have information collected from the routine anesthesia and surgical records such as oxygen levels during surgery, length of surgery and lung-related complications within 7 days after surgery

Conditions

  • Lung Collapse
  • One-lung Ventilation
  • Thoracic Anesthesia
  • Thoracic Surgery, Video-assisted
  • Double-lumen Tube
  • Uniportal Video Assisted Thoracic Surgery (U-VATS)
  • Postoperative Pulmonary Complications

Interventions

OTHER

bronchial suction

Bronchial suction will be performed through the operative lumen of the double-lumen endobronchial tube on two occasions: before pleural opening, and immediately after pleural opening. The suction pressure is at -30 cmH2O and each suction period will last for 60 seconds.

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Nattaya Raykateeraroj, MD · Siriraj Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-08-31
Primary Completion
2028-07-31
Completion
2028-07-31

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07660588 on ClinicalTrials.gov