Selective Lobar Blockade and Bronchial Blockers

Summary

Selective lobar blockade (SLB) is a specific technique that allows collapse of the operated lobe during thoracic surgery while the other lobes are ventilated. It is associated with the improvement of arterial oxygenation during one lung ventilation (OLV) for thoracic with providing adequate surgical access. The purpose of this study is to compare the efficacy of three bronchial blockers, namely an Arndt® wire-guided endobronchial blocker, a Cohen Flexi-tip endobronchial blocker or a Fuji Uni-blocker, for achieving selective lobar collapse.

Conditions

• Elective Thoracic Surgery
• One Lung Ventilation

Interventions

DEVICE

Endobronchial double lumen tube

Endobronchial double lumen tube for one lug ventilation

DEVICE

Arndt® blocker

Arndt® blocker for selective lobar deflation

DEVICE

Cohen blocker

Cohen blocker for selective lobar deflation

DEVICE

Fuji Uni-blocker

Fuji Uni-blocker foe selective lobar deflation

Sponsors & Collaborators

• Imam Abdulrahman Bin Faisal University

  lead OTHER

Principal Investigators

• Abdulmohsen Al Ghamdi, MD · Associate Professor, of Anesthesia and Surgical ICU, University of Dammam, Al Khubar, Saudi Arabia

• Mohammed Abdul Shafi, MD · Assistant Professor of Anesthesia and Surgical ICU, University of Dammam, Al Khubar, Saudi Arabia.

• Haytham Zien, MD · Assistant Professor of Anesthesia and Surgical ICU, Dammam University

• Alaa M Khidr, MD · Assistant Professor Anaesthesiology and Surgical ICU, King Fahd Hospital of the University of Dammam, Al Khubar, Saudi Arabia

• Yasser F El Ghoneimy, MD · Associate Professor of Cardiothoracic Surgery, King Fahd Hospital of the University of Dammam, Al Khubar, Saudi Arabia.

• Mohamed A Regal, MD · Associate Professor of Cardiothoracic Surgery, King Fahd Hospital of the University of Dammam, Al Khubar, Saudi Arabia.

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-01-31

Primary Completion

2016-08-31

Completion

2016-09-30

Countries

• Saudi Arabia

Study Locations