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Driving Pressure Limited Ventilation During Video-assisted Thoracoscopic Lobectomy

NCT03177564 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2017-06-06

No results posted yet for this study

Summary

This study aims to investigate the feasibility of a driving pressure limited mechanical ventilation strategy compared to a conventional strategy in patients undergoing one-lung ventilation during Video-assisted thoracoscopic lobectomy.

Conditions

  • Pulmonary Complication
  • Thoracic Surgery

Interventions

PROCEDURE

Protective ventilation 1

Low tidal volume, high inspired oygen fraction (FiO2) and recruitment maneuver.

PROCEDURE

Protective ventilation 2

Low tidal volume, PEEP, moderate inspired oygen fraction (FiO2) and recruitment maneuver.

PROCEDURE

Driving Pressure Limited Ventilation

Positive end expiratory pressure is adjusted to minimize driving pressure, plateau pressure minus end expiratory pressure from 3 to 10 cmH2O during one-lung ventilation and a FiO2 of 60%

Sponsors & Collaborators

  • The Affiliated Hospital of Xuzhou Medical University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-05
Primary Completion
2018-06-10
Completion
2018-06-10

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03177564 on ClinicalTrials.gov