Rhythm Psychophysics With Parkinson's Patients
NCT07647913 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2026-06-15
Summary
The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:
* Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information?
* Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information?
* Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information?
Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.
Conditions
- Parkinson Disease(PD)
Interventions
- DRUG
-
Withholding Levodopa
Participants will have to withhold Levodopa medication 12 h before one of two experimental sessions.
Sponsors & Collaborators
- lead OTHER
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-01
- Primary Completion
- 2027-09-30
- Completion
- 2027-10-31
Countries
- Canada
Study Locations
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