Rhythm Psychophysics With Parkinson's Patients

NCT07647913 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-06-15

No results posted yet for this study

Summary

The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:

* Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information?
* Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information?
* Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information?

Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.

Conditions

  • Parkinson Disease(PD)

Interventions

DRUG

Withholding Levodopa

Participants will have to withhold Levodopa medication 12 h before one of two experimental sessions.

Sponsors & Collaborators

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2027-09-30
Completion
2027-10-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07647913 on ClinicalTrials.gov