Human Observatory Study

Summary

The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level. Individual multi-system clinical data from enrolled participants are linked to a continuously-ingested ecological data infrastructure spanning environmental exposures, social determinants, genealogical and family history records, mortality data, and population health databases at geographic resolutions from home address to global scale and beyond. The resulting model generates individual screening recommendations informed by population-level causal estimates, and population-level causal forecasts anchored by present-timepoint individual clinical biology. Thus creating a feedback architecture designed to improve both simultaneously.

Conditions

• Aging
• Mortality
• All-cause Mortality
• Life Expectancy
• Cardiovascular Diseases
• Neoplasms
• Cognitive Dysfunction
• Metabolic Syndrome
• Frailty
• Musculoskeletal Disease
• Neurodegenerative Disease
• Dementia
• Activities of Daily Living
• Health Related Quality of Life
• Disability Physical
• Environmental Exposure
• Occupational Diseases
• Health Equity
• Social Determinants of Health

Interventions

OTHER

Multi-Domain Ecological and Clinical Data Linkage

Linkage of individual multi-system clinical health measurements to continuously-ingested ecological data from public and private registries spanning environmental, social, genealogical, and population health domains at geographic resolutions from home address to global scale and beyond. The linked dataset feeds a continuously-updating causal inference engine generating life expectancy estimates, disease cluster detection, individual screening recommendations, and population health intelligence.

Sponsors & Collaborators

• Longevity Metrics, Inc.

  lead INDUSTRY

Principal Investigators

• William Brandenburg, MD · Longevity Metrics

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2026-04-25

Primary Completion

2099-12-31

Completion

2099-12-31

Countries

• United States

Study Locations