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Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath Diameter

NCT07632287 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2026-06-08

No results posted yet for this study

Summary

The purpose of this study is to compare the effects of the standard Trendelenburg position and the modified Z-Trendelenburg position on cerebral oxygenation and optic nerve sheath diameter (ONSD) in patients undergoing laparoscopic surgery. The prolonged use of the standard Trendelenburg position combined with pneumoperitoneum can increase intracranial pressure and affect cerebral blood flow. In this study, researchers will use non-invasive methods, including Near-Infrared Spectroscopy (NIRS) to monitor regional cerebral oxygenation, and ocular ultrasonography to measure ONSD as an indicator of intracranial pressure changes. The main goal is to determine whether the modified Z-Trendelenburg position serves as a safer physiological alternative by reducing these potential adverse effects compared to the standard position.

Conditions

  • Laparoscopic Gynecological Surgery

Interventions

PROCEDURE

Standard Trendelenburg Position

Placement of the patient in the traditional straight head-down tilt position required for laparoscopic surgical access and pneumoperitoneum

PROCEDURE

Modified Z-Trendelenburg Position

Placement of the patient in a modified head-down tilt position combined with leg flexion

Sponsors & Collaborators

  • Ankara Etlik City Hospital

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-06
Primary Completion
2026-05-18
Completion
2026-05-18

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07632287 on ClinicalTrials.gov