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Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

NCT07525648 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 63

Last updated 2026-05-19

No results posted yet for this study

Summary

Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP).

Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP.

This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.

Conditions

  • Intracranial Pressure
  • Laparoscopic Surgery
  • Optic Nerve Sheath Diameter

Interventions

DRUG

Sevoflurane

Anesthesia maintenance will be provided with sevoflurane at 1 MAC in a 40% oxygen-air mixture.

DRUG

Desflurane

Anesthesia maintenance will be provided with desflurane at 1 MAC in a 40% oxygen-air mixture.

Sponsors & Collaborators

  • Medipol University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-15
Primary Completion
2026-05-10
Completion
2026-05-15

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07525648 on ClinicalTrials.gov