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Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.

NCT07619508 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100000

Last updated 2026-07-09

No results posted yet for this study

Summary

Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.

Conditions

Interventions

DRUG

Tirzepatide

Initiation of tirzepatide described in electronic health records is used as the exposure.

DRUG

Semaglutide

Initiation of injectable semaglutide described in electronic health records is used as the reference.

Sponsors & Collaborators

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • Shirley Wang, PhD, ScM · Brigham and Women's Hospital

  • Nils Krüger, MD · Brigham and Women's Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-10
Primary Completion
2026-06-01
Completion
2026-06-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07619508 on ClinicalTrials.gov