Effect of Diosmin/Hesperidin Combination on Platinum Compounds-Induced Nephropathy in Cancer Patients
NCT07598214 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2026-05-20
Summary
The current study aims to investigate the protective properties of diosmin/hesperidin on cisplatin-induced nephrotoxicity.
Conditions
- Cancer Patients
Interventions
- COMBINATION_PRODUCT
-
diosmin/hesperdin
combination of Diosmin and Hesperidin
Sponsors & Collaborators
-
Beni-Suef University
lead OTHER
Principal Investigators
-
marwa mohsen · clinical pharmacy department, Beni Suef University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-03
- Primary Completion
- 2026-11-03
- Completion
- 2026-12-03
Countries
- Egypt
Study Locations
More Related Trials
-
Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer Patients
NCT06297369 ·Status: RECRUITING ·Phase: PHASE2
-
Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity
NCT07564479 ·Status: RECRUITING ·Phase: PHASE2
-
L-Carnitine Protective Effect in Nephrotoxicity
NCT07108777 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluation of the Effect of Acetazolamide, Mannitol and N-acetylcysteine on Cisplatin-Induced Nephrotoxicity
NCT02760901 ·Status: COMPLETED ·Phase: PHASE2
-
Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity
NCT07476443 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Protective Effect of N-acetylcysteine on Oxaliplatin-Induced Neuropathy in Colorectal Cancer
NCT07391163 ·Status: COMPLETED ·Phase: NA
-
Preloading Magnesium Attenuate Cisplatin-induced Nephrotoxicity
NCT02481518 ·Status: COMPLETED ·Phase: PHASE4
-
Oxaliplatin - Induced Peripheral Neuropathy in Patients With Gastrointestinal Tract Cancer
NCT02428101 ·Status: ENROLLING_BY_INVITATION
-
Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients
NCT05510856 ·Status: COMPLETED ·Phase: PHASE4
-
The Possible Protective Role of Ketotifen Against Oxaliplatin Induced Peripheral Neuropathy
NCT05624138 ·Status: RECRUITING ·Phase: PHASE3
-
Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)
NCT04780854 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients
NCT05351021 ·Status: COMPLETED ·Phase: PHASE2
-
Nerve Excitability in Cisplatin-Induced Peripheral Neuropathy
NCT07095998 ·Status: RECRUITING ·Phase: NA
-
"The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients"
NCT06679387 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Cisplatin-Induced Peripheral Neuropathy in Patients With Germ Cell Tumor
NCT02677727 ·Status: COMPLETED
-
Pentoxifylline Role Against Chemotherapy-induced Neuropathy
NCT06562998 ·Status: COMPLETED ·Phase: NA
-
Fenofibrate Role in Breast Cancer Patients
NCT05813145 ·Status: COMPLETED ·Phase: NA
-
Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
NCT06091553 ·Status: RECRUITING ·Phase: PHASE2
-
Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer
NCT04205071 ·Status: WITHDRAWN ·Phase: PHASE1
-
N-acetyl Cysteine Effect in Peripheral Neuropathy in Cancer Patients
NCT03492047 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Role of N-Acetylcysteine for Prevention of Cisplatin-induced Nephrotoxicity
NCT06019520 ·Status: UNKNOWN ·Phase: NA
-
Nutritional Supplement for Treating Chemotherapy Induced Neuropathy
NCT07022938 ·Status: COMPLETED ·Phase: PHASE4
-
Cannabidiol for Prevention of Chemotherapy-induced Peripheral Neuropathy
NCT04582591 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy-induced Peripheral Neuropathy (CIPN) on Motor and Sensory Function
NCT04799080 ·Status: COMPLETED
-
Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy
NCT06459193 ·Status: COMPLETED ·Phase: PHASE1/PHASE2