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Chemotherapy-induced Peripheral Neuropathy (CIPN) on Motor and Sensory Function

NCT04799080 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2024-04-01

No results posted yet for this study

Summary

As cancer survival rates have been increased due to technological developments and early detection strategies, there has been been a growing need to assess the effect of long-term complications and adverse effects upon patients' functionality and quality of life. Chemotherapy, which is accepted to be the body of systemic adjuvant therapy is attributed to long-term survival, yet some side effects such as sarcopenia, loss of muscle strength and functional capacity, fatigue, and sensory disturbances due to the neurotoxic effects have been well known. Chemotherapy-induced peripheral neuropathy (CIPN) is a condition that is characterized by main loss of cutaneous sensation especially in the distal part of the extremities. CIPN affects approximately 30-40% of patients with cancer undergoing chemotherapy. Loss of sensation in distal sides of upper and lower extremities may cause not only deterioration of fine hand skills but also loss of balance and thereby one's mobility and independence are detrimentally affected. Thus, this study is aimed to assess CIPN in patients with cancer undergoing chemotherapy in a longitudinal design by assessing the cutaneous function of the sensory nerves and related effect of motor function.

Conditions

  • Cancer
  • Chemotherapy-induced Peripheral Neuropathy
  • Chemotherapeutic Toxicity
  • Breast Cancer
  • Breast Neoplasms
  • Colon Neoplasm
  • Colo-rectal Cancer

Sponsors & Collaborators

  • Izmir Bakircay University

    lead OTHER

Principal Investigators

  • Murat Akyol, MD · Bakircay University Faculty of Medicine Department of Internal Medicine, Medical Oncology unit

  • Zeynep Arıbaş, PT · Bakircay University Faculty of Health Sciences Department of Physical Therapy and Rehabilitation

  • Alper Tuğral, PT, MSc · Bakircay University Faculty of Health Sciences Department of Physical Therapy and Rehabilitation

  • Yeşim Bakar, PT, Prof · Bakircay University Faculty of Health Sciences Department of Physical Therapy and Rehabilitation

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-06
Primary Completion
2022-03-15
Completion
2022-05-15

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04799080 on ClinicalTrials.gov