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L-carnosine Prophylactic Effect on Oxaliplatin Induced Peripheral Neuropathy in GIT Cancer Patients

NCT02808624 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2017-04-24

No results posted yet for this study

Summary

This study evaluates the prophylactic effect of exogenous L-CARNOSINE in Oxaliplatin induced peripheral neuropathy, Thus half of the patients will receive L-CARNOSINE with Oxaliplatin and the other half will not receive L-CARNOSINE with their chemotherapy (oxaliplatin),And then neuropathy together with some oxidative stress markers will be assessed at the end of treatment duration (three months) .

Conditions

Interventions

DRUG

L-CARNOSINE

L-CARNOSINE is a supplement given with chemotherapy to prevent peripheral neuropathy.

Sponsors & Collaborators

  • Misr International University

    collaborator OTHER

  • Ain Shams University

    collaborator OTHER

  • Cairo University

    lead OTHER

Principal Investigators

  • Samira Saleh, Professor · Cairo University

  • Hanan elabhar, Professor · Cairo University

  • Mona Schaalan, assoc. prof. · Misr International University

  • Amr Shafik, Assoc. Prof · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-06-30
Primary Completion
2016-11-30
Completion
2016-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02808624 on ClinicalTrials.gov