Mesenchymal Stem Cells in the Treatment of Burn Wounds
NCT07580755 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2026-05-12
Summary
Burn patients were randomly divided into the low-dose stem cell gel group, the high-dose stem cell gel group, and the placebo group (with only the gel), and received the same treatment under the same conditions simultaneously.
Conditions
- Burn Injury
- Burn Patients
Interventions
- COMBINATION_PRODUCT
-
low-dose stem cell gel group
Using hydrogels containing low-doses of placenta-derived mesenchymal stem cells as wound dressings to promote wound healing in burn patients after thick skin grafting
- COMBINATION_PRODUCT
-
high-dose stem cell gel group
Using hydrogels containing or without differenthigh-doses of placenta-derived mesenchymal stem cells as wound dressings to promote wound healing in burn patients after thick skin grafting
- OTHER
-
with only the gel
Using only hydrogels as wound dressings to promote wound healing in burn patients after thick skin grafting
Sponsors & Collaborators
-
The First Affiliated Hospital of Xinxiang Medical College
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-27
- Primary Completion
- 2027-12-31
- Completion
- 2028-12-31
Countries
- China
Study Locations
More Related Trials
-
Stem Cell Therapy to Improve Burn Wound Healing
NCT02104713 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Exploratory Efficacy Study of Collagen Membrane With Mesenchymal Stem Cells in the Treatment of Skin Defects
NCT02672280 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
NCT05984628 ·Status: RECRUITING ·Phase: NA
-
Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Poorly Healed Wounds of Postoperative Incision
NCT04538885 ·Status: UNKNOWN ·Phase: PHASE1
-
Mesenchymal Stem Cell-derived Pleiotropic Factor in the Treatment of Donor Sites
NCT04234750 ·Status: UNKNOWN ·Phase: PHASE1
-
Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology
NCT05275335 ·Status: RECRUITING
-
MSCs for the Treatment of Burn Wounds
NCT06103409 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1/PHASE2
-
Cell Suspension With Biologic Dressing for Burn Wounds
NCT07555418 ·Status: NOT_YET_RECRUITING
-
Clinical Efficacy and Safety of Autologous Cultured Keratinocyte Cell on Severe Burn Wood
NCT00978705 ·Status: UNKNOWN ·Phase: PHASE3
-
Treatment of Pressure Ulcers Using Biological Skin Substitutes
NCT06853210 ·Status: COMPLETED ·Phase: NA
-
Research on the Key Technology of Burn Wound Treatment
NCT03279549 ·Status: UNKNOWN ·Phase: NA
-
A Phase I, Single-blind, Randomized Study of the Safety and Efficacy of Cellularized Integra® Using Autologous Burn-derived Stem Cells
NCT05344521 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Treatment of Patients With Skin Burns Using Keratinocytes and Skin Fibroblasts
NCT04485962 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Extracorporeal Shock Wave Therapy for Burn Scar Charateristics
NCT04187586 ·Status: COMPLETED
-
Efficacy of a Fibrin Sealant in Burn Surgery
NCT00181974 ·Status: COMPLETED ·Phase: NA
-
Regenerative Cellular Therapies, Physiology, Pathology and Developmental Biology
NCT02469207 ·Status: UNKNOWN
-
The Relationship of Body Function, Participation and Quality of Life in Patients With Burn: A Longitudinal Study
NCT02950675 ·Status: COMPLETED
-
Development and Clinical Study of Burn Wound Nursing Dressing Based on Sodium Hyaluronate Carbomer Composite Hydrogel
NCT07568600 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Post-Burn Raw Area
NCT03686449 ·Status: UNKNOWN ·Phase: NA
-
Plasma Therapy for Diverse Wounds
NCT07553689 ·Status: NOT_YET_RECRUITING
-
Assessment of Mechanisms of Improved Wound Healing
NCT00673309 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Plasma Therapy for Scar Management
NCT07548593 ·Status: NOT_YET_RECRUITING
-
Retrospective Analysis of Spray Skin Treats for Severe Burns
NCT06170424 ·Status: COMPLETED
-
Hypertrophic Scarring After Facial Burn
NCT00242970 ·Status: COMPLETED
-
Long Term Evaluation of Human Acellular Dermal Matrix Allograft For Coverage of the Wound After Extensive Deep Burn
NCT01562119 ·Status: UNKNOWN