Adult Stem Cell Response to Burn Injury
NCT00609661 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2012-10-08
Summary
This study is designed to determine the response of adult stems cells, also referred to as mesenchymal stem cells (MSCs), to tissue injury resulting from thermal burns. The study will consist of a one time collection of a patient's blood, about one teaspoon, on the third day following the initial burn. MSCs in the blood will then be quantitated and identified using according to unique proteins found on their cell surface using flow cytometry. The results of flow cytometry analysis will then be compared to the patients characteristics (age, sex, race, etc.), their past medical history (hx of diabetes, hypertension, heart disease, etc.) and to the patient outcome (length of hospital stay, mortality, etc.).
Conditions
- Wound Healing
- Burn
Sponsors & Collaborators
-
Ohio State University
lead OTHER
Principal Investigators
-
Chandan K Sen, PhD · Ohio State University
-
Daniel P Zelinski, MD, PhD · Ohio State University
-
Sorabh Khandelwal, MD · Ohio State University
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-02-29
- Primary Completion
- 2010-02-28
- Completion
- 2010-06-30
More Related Trials
-
CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
NCT02994654 ·Status: COMPLETED ·Phase: NA
-
Umbilical Cord Mesenchymal Stem Cells for the Repair of Large Area Burn Wounds
NCT06122532 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries
NCT01138917 ·Status: COMPLETED ·Phase: NA
-
Allogeneic ADSCs and Platelet-Poor Plasma Fibrin Hydrogel to Treat the Patients With Burn Wounds (ADSCs-BWs)
NCT03113747 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
ST266 Versus Standard Care In Treating Partial Thickness Burns
NCT00886470 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Feasibility of Obtaining ADRCs From Discarded Thermal Burn Eschar Tissue Using Investigational Celution® System
NCT02362386 ·Status: COMPLETED
-
Large Burn Outcome Study
NCT00731887 ·Status: WITHDRAWN
-
Evaluating MMPs in Burns
NCT03148977 ·Status: TERMINATED
-
ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
NCT02380612 ·Status: COMPLETED ·Phase: NA
-
Understanding Coagulation and Inflammation in Burns
NCT03077269 ·Status: TERMINATED
-
Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Post-Burn Raw Area
NCT03686449 ·Status: UNKNOWN ·Phase: NA
-
Identification and Validation of Biomarkers for Infections in Burns
NCT02457663 ·Status: TERMINATED
-
Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients
NCT05652816 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Hypoxia-inducible Factor-1 (HIF-1) Regulated Circulating Angiogenic Cells (CACs) Recruitment in Burn Wound Healing
NCT00796627 ·Status: TERMINATED ·Phase: NA
-
Soluble Factors in the Serum of Severely Burned Patients
NCT02549079 ·Status: COMPLETED
-
Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology
NCT05275335 ·Status: RECRUITING
-
Examine the Validity of a Panel of Objective Burn Scar Measurement Tools
NCT05126017 ·Status: UNKNOWN
-
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients
NCT04252651 ·Status: UNKNOWN
-
Pilot Study of Azficel-T for the Treatment of Restrictive Burn Scars
NCT01858753 ·Status: TERMINATED ·Phase: PHASE2
-
Use of Platelet-rich Plasma in Second-degree Superficial Burns
NCT04276818 ·Status: COMPLETED ·Phase: NA
-
Microsurfaced Grafts in Deep Burn Wounds
NCT04589442 ·Status: RECRUITING ·Phase: PHASE4
-
CO2 Laser Revision for Burn Related Donor Site Scars
NCT04456127 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Efficacy of a Fibrin Sealant in Burn Surgery
NCT00181974 ·Status: COMPLETED ·Phase: NA
-
Evaluation of ACell Hydrated Wound Dressing for Autogenous Skin Donor Sites
NCT00352729 ·Status: WITHDRAWN ·Phase: NA
-
Evaluation Perioperative Nutrition on Donor Site Healing in Patients Undergoing Reconstructive Burn Surg
NCT00539097 ·Status: TERMINATED ·Phase: PHASE2/PHASE3