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Allogenic Stem Cell Therapy in Patients With Acute Burn

NCT01443689 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2012-11-28

No results posted yet for this study

Summary

Burn trauma,especially extensive ones, remains a life-threatening local and general inflammatory condition destroying the skin and underlying tissues, and resulting in serious sequelae. Remarkable progress has been achieved during last 30 years，stem cell therapy plays an important role in this progress. Human umbilical cord mesenchymal stem cells (hUCMSCs) and human cord blood mononuclear cells (hCBMNCs) have been shown to have the ability to modulate the immune response and enhance angiogenesis, suggesting the novel and promising therapeutic strategy for burn. In this study, the safety and efficacy of hUCMSCs and hCBMNCs transplantation will be evaluated in patients with acute burn.

Conditions

  • Burns

Interventions

BIOLOGICAL

human umbilical cord mesenchymal stem cells

Participants will be given conventional therapy plus hUCMSCs transplantation.

BIOLOGICAL

human cord blood mononuclear cells and human umbilical cord mesenchymal stem cells

Participants will be given conventional therapy plus and hCBMNCs and hUCMSCs transplantation.

DRUG

Conventional therapy

Participants will be given conventional therapy only.

Sponsors & Collaborators

  • The Second Affiliated Hospital of Kunming Medical University

    collaborator OTHER

  • Shenzhen Beike Bio-Technology Co., Ltd.

    lead INDUSTRY

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-07-31
Primary Completion
2013-03-31
Completion
2013-07-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01443689 on ClinicalTrials.gov