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Characterization of the Methylation Profile of Stored Human Samples

NCT07573072 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2026-05-07

No results posted yet for this study

Summary

The project, funded by the PNRR under Mission 4 "Education and Research," aims to strengthen the network of Italian biobanks by improving data management in accordance with the FAIR principles (Findable, Accessible, Interoperable, Reusable). The University of Trento has issued a call for proposals to support Italian biobanks in characterizing samples and expanding associated datasets using advanced technologies.

The Biological Resource Center at the Rizzoli Orthopedic Institute in Bologna participated in this call for proposals, requesting funding to analyze the DNA methylation profiles of three patient cohorts: those with inflammatory/degenerative diseases, sarcomas, and rare genetic musculoskeletal disorders. This study will contribute to understanding the biological significance of methylation and exploring its diagnostic and therapeutic potential.

The initiative aims to generate data useful for personalized medicine and improve the management of the diseases involved.

Conditions

  • Rare Disorders
  • Sarcoma of Bone and Connective Tissue
  • Inflammatory Articular Diseases

Sponsors & Collaborators

  • Istituto Ortopedico Rizzoli

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-28
Primary Completion
2025-07-22
Completion
2025-07-22

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07573072 on ClinicalTrials.gov