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Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM.

NCT01079429 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1200

Last updated 2021-04-15

No results posted yet for this study

Summary

The purpose of this study is to describe DNA copy number variations and gene expression profiles of bone marrow plasma cells of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). The final objective is to search for correlations with the risk of progression in order to establish a predictive model of early malignant transformation.

Conditions

  • Monoclonal Gammopathy of Undetermined Significance
  • Smoldering Myeloma

Interventions

GENETIC

Genetic study of DNA copies

Gene expression profiling, DNA copy number variation

Sponsors & Collaborators

  • Intergroupe Francophone du Myelome

    collaborator NETWORK

  • Rennes University Hospital

    lead OTHER

Principal Investigators

  • Olivier DECAUX, MD · Rennes University Hospital

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-01-12
Primary Completion
2014-01-31
Completion
2019-09-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01079429 on ClinicalTrials.gov