Load Incorporating Cardiac Assessment by Echocardiography In Patients With SEpsis (LIAISE Study)
NCT07562217 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2026-05-01
Summary
The LIAISE study is a prospective observational study comparing the performance of load-incorporating echocardiographic parameters and conventional parameters in predicting adverse events among adult patients presenting to the ICU with sepsis. It will be conducted in hospitals in Australia, Hong Kong, South Africa, and Canada, with 199 patients recruited over 2 years. All included patients will receive an regular echocardiographic assessment and their haemodynamic parameters will be simultaneously recorded. Participants will be followed for up to 1 year after enrolment. Load incorporating parameters will be derived from regularly obtained echocardiography and haemodynamic data during offline analysis. The predictive value of cardiac parameters will be evaluated based on their statistical association with clinical outcomes.
Conditions
Sponsors & Collaborators
-
Queen Mary Hospital, Hong Kong
collaborator OTHER -
The University of Queensland
lead OTHER
Principal Investigators
-
Hideaki Nonaka, Dr · The University of Queensland
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2027-12-31
- Completion
- 2028-11-30
Countries
- Australia
Study Locations
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