Load Incorporating Cardiac Assessment by Echocardiography In Patients With SEpsis (LIAISE Study)
NCT07562217 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2026-05-01
Summary
The LIAISE study is a prospective observational study comparing the performance of load-incorporating echocardiographic parameters and conventional parameters in predicting adverse events among adult patients presenting to the ICU with sepsis. It will be conducted in hospitals in Australia, Hong Kong, South Africa, and Canada, with 199 patients recruited over 2 years. All included patients will receive an regular echocardiographic assessment and their haemodynamic parameters will be simultaneously recorded. Participants will be followed for up to 1 year after enrolment. Load incorporating parameters will be derived from regularly obtained echocardiography and haemodynamic data during offline analysis. The predictive value of cardiac parameters will be evaluated based on their statistical association with clinical outcomes.
Conditions
Sponsors & Collaborators
-
Queen Mary Hospital, Hong Kong
collaborator OTHER -
The University of Queensland
lead OTHER
Principal Investigators
-
Hideaki Nonaka, Dr · The University of Queensland
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2027-12-31
- Completion
- 2028-11-30
Countries
- Australia
Study Locations
More Related Trials
-
Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis
NCT01995448 ·Status: COMPLETED
-
Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock
NCT06993948 ·Status: COMPLETED
-
Place of Echocardiography in IV Fluid Therapy in Patients With Septic Shock and Left Ventricular Systolic Dysfunction
NCT02899897 ·Status: COMPLETED
-
Cardiovascular Phenotypes in Sepsis
NCT07442032 ·Status: NOT_YET_RECRUITING
-
Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock
NCT01188993 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparative Study Between Neutrophil/Lymphocyte Ratio and Lactate/Albumin Ratio as Predictive Inflammatory Markers for Sepsis
NCT07089524 ·Status: RECRUITING
-
Myocardial Contrast Echocardiography in Septic Patients
NCT04397640 ·Status: UNKNOWN ·Phase: NA
-
Change in MAPSE During Treatment of Sepsis
NCT05634733 ·Status: RECRUITING
-
Establishment of Early Diagnosis and Monitoring Model for Sepsis Patients
NCT04974411 ·Status: UNKNOWN
-
Immune Responses to Dengue and Sepsis
NCT07040202 ·Status: RECRUITING
-
Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants
NCT05552521 ·Status: COMPLETED
-
Thromboelastography in in Patients With Sepsis
NCT00994877 ·Status: UNKNOWN
-
Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis
NCT06491966 ·Status: RECRUITING
-
Ultrasound Optimization of Initial Fluid Challenge in Sepsis
NCT04028102 ·Status: UNKNOWN
-
ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS)
NCT05922371 ·Status: COMPLETED
-
Extended vs. Intermittent Beta-Lactam Infusion in ICU Sepsis
NCT07398703 ·Status: NOT_YET_RECRUITING
-
A Prospective Observational Study of Sepsis
NCT05309889 ·Status: UNKNOWN
-
Using AI to Improve Sepsis Quality of Care in the Emergency Department
NCT07581340 ·Status: COMPLETED ·Phase: NA
-
Identification and Clinical Efficacy Analysis of Biomarkers in Sepsis Patients
NCT05911711 ·Status: UNKNOWN
-
Sensitivity and Specificity of Leucocytes Profiling Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
NCT06612307 ·Status: COMPLETED
-
Molecular Early Sepsis Identification Study
NCT05833412 ·Status: UNKNOWN
-
Sepsis and Myocarditis
NCT07079605 ·Status: RECRUITING
-
Role of RNA Metabolism Alterations in Persistent Immune Dysfunction After Sepsis
NCT07418801 ·Status: NOT_YET_RECRUITING
-
Prognostic Assessment of Diastolic and Systolic Left Ventricular Function in Septic Shock
NCT02918214 ·Status: COMPLETED
-
N\L Ratio Versus L\A Ratio as a Predictor of Morbidity and Mortality in Sepsis and Septic Shock
NCT05825118 ·Status: UNKNOWN