Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
NCT07548099 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2026-05-22
Summary
This research study is being conducted to test how an imaging drug called 64Cu-DOTA-ECL1i can be used to image an abdominal aortic aneurysm. 64Cu-DOTA-ECL1i is a drug used with an imaging test called a PET/CT (Positron Emission Tomography/Computed Tomography).
The aim is to collect data using a new imaging drug called 64Cu-DOTA-ECL1i that may be able to create images of inflammation in the aorta, which is thought to be important in how aneurysms grow and develop and to understand how consistent these scans are across time and what might affect the inflammation.
Conditions
- Abdominal Aortic Aneurysm
Interventions
- DRUG
-
64Cu-DOTA-ECL1i
The radiotracer 64Cu-DOTA-ECL1i will be used to assess the aortic wall in individuals with AAA and age-matched participants without a diagnosis of AAA as a control group.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Scott M Damrauer, MD · Penn Medicine Division of Vascular Surgery
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-04-30
- Primary Completion
- 2028-04-30
- Completion
- 2029-04-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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