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18F Sodium Fluoride PET/CT in Acute Aortic Syndrome

NCT03647566 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 76

Last updated 2022-03-14

No results posted yet for this study

Summary

The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to predict disease progression in acute aortic syndrome.

Conditions

  • Acute Aortic Syndrome
  • Aortic Dissection
  • Penetrating Aortic Ulcer
  • Intramural Hematoma

Interventions

DIAGNOSTIC_TEST

18F Sodium Fluoride Positron Emission Tomography / Computed Tomography

PET scan using the 18F-Sodium Fluoride radiotracer followed by an attenuation correction CT scan

DIAGNOSTIC_TEST

CT Aortic Angiogram

CT scan to assess aortic morphology and contextualise PET scan

DIAGNOSTIC_TEST

Aortic MRI

Aortic MRI to assess aortic morphology and contextualise PET scan

Sponsors & Collaborators

  • NHS Lothian

    collaborator OTHER_GOV

  • British Heart Foundation

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Maaz BJ Syed, MBChB MSc · University of Edinburgh

Eligibility

Min Age
25 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-01
Primary Completion
2021-02-01
Completion
2021-02-01

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03647566 on ClinicalTrials.gov