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Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure

NCT07527156 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2026-04-14

No results posted yet for this study

Summary

This study will evaluate the feasibility and safety of achieving therapeutic concentrations of beta-hydroxybutyrate using continuous infusion of D-beta-hydroxybutyrate monoester administered via a nasogastric tube in patients with acutely decompensated heart failure with reduced left ventricular ejection fraction.

Conditions

  • Acute Heart Failure (AHF)
  • Cardiogenic Shock
  • Heart Failure
  • Ketones
  • Ketone Body Metabolism

Interventions

DIETARY_SUPPLEMENT

Ketone Monoester (KE)

Continous infusion of a commercially available ketone monoester via nasogastric tube.

Sponsors & Collaborators

  • Institute for Clinical and Experimental Medicine

    lead OTHER_GOV

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-04
Primary Completion
2027-03-31
Completion
2027-03-31

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07527156 on ClinicalTrials.gov