The Effects of a High Fat and Low Carbohydrate Diet on Clinical Status in Patients With Heart Failure

Summary

The aim of the present study was to evaluate the effects of a high fat, low carbohydrate (CHO) diet on clinical status during 60 days of follow-up in patients with stable heart failure (HF).

In a randomized controlled clinical trial 44 ambulatory patients with HF were included, assigned to an intervention (40% CHO, 40% fat and 20% protein; n=22) or control groups (50% CHO, 30% fat, 20% protein; n=20). Both groups received recommended pharmacological management. At baseline and at 2 months of follow-up, the variables evaluated were: body composition, handgrip strength, oxygen saturation, dietary intake, clinical data, lipid profile, plasma glucose and exercise tolerance

Conditions

• Heart Failure

Interventions

OTHER

High fat and low carbohydrate diet

high fat and low carbohydrate diet. At baseline and at 2 month of following, the variables that were evaluated,

OTHER

Control diet

Control diet. At baseline and at 2 month of following, the variables that were evaluated,

Sponsors & Collaborators

• Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

  lead OTHER

Principal Investigators

• Dulce G Gonzalez, M.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Lilia Castillo, M.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Arturo Orea, MD · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Gabriela Olvera, B.Sc · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Karla Balderas, B.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Cira Santillán, M.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

• Wendy Rodríguez, M.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-05-31

Primary Completion

2012-12-31

Completion

2013-03-31

Countries

• Mexico

Study Locations