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Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions

NCT07212543 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 72

Last updated 2025-12-09

No results posted yet for this study

Summary

This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies:

Cause differences in the Bispectral Index (BIS), which measures brain activity during anesthesia, Affect postoperative cognitive functions such as memory and attention.

Participants will:

Receive desflurane anesthesia during surgery, Have anesthesia delivered at different low-flow rates, Have their BIS values monitored throughout the operation, Complete tests after surgery to evaluate their cognitive functions.

This research will help determine the safety of different low-flow strategies and their impact on patients' cognitive recovery after surgery.

Conditions

  • Major Abdominal Surgeries

Interventions

OTHER

Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.

Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.

Sponsors & Collaborators

  • Dolunay ARIK

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-15
Primary Completion
2025-12-20
Completion
2025-12-21

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07212543 on ClinicalTrials.gov