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Glycemic Markers for Predicting Gestational Diabetes in Pregnant Women With Previous Bariatric Surgery

NCT07517406 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 84

Last updated 2026-04-08

No results posted yet for this study

Summary

Gestational diabetes mellitus (GDM) is associated with significant maternal and fetal complications. The standard diagnostic test for GDM is the 75-gram oral glucose tolerance test (OGTT). However, pregnant women who have undergone bariatric surgery may not tolerate OGTT due to dumping syndrome and gastrointestinal side effects. This creates diagnostic challenges in this specific population.

The aim of this prospective observational study is to evaluate whether routinely measured glycemic markers, including fasting blood glucose, postprandial blood glucose, HbA1c, and urinary glucose levels, can predict the development of gestational diabetes mellitus and related pregnancy complications in women with prior bariatric surgery.

Pregnant women aged 18-50 years with a history of bariatric surgery will be enrolled and followed throughout pregnancy. The predictive value of glycemic markers for GDM, macrosomia, and polyhydramnios will be analyzed using multivariable logistic regression models.

This study aims to provide alternative diagnostic approaches for GDM screening in pregnant women who are unable to tolerate OGTT and to contribute to improving maternal and perinatal outcomes in this growing patient population.

Conditions

  • Gestational Diabetes Mellitus (GDM)
  • Pregnancy Complications
  • History of Bariatric Surgery

Sponsors & Collaborators

  • Burak Deniz Aydoğdu

    lead OTHER

Principal Investigators

  • Burak Deniz AYDOĞDU, MD · Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Obstetrics and Gynecology

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-01
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07517406 on ClinicalTrials.gov