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Can Genetic Markers Predict Weight Loss After Gastric By-pass Surgery

NCT01736384 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2020-02-28

No results posted yet for this study

Summary

There is a variability in weight loss after gastric bypass surgery for obesity despite a standardised surgical procedure. This study aims to investigate if genetic markers can predict outcome after gastric by-pass surgery in treatment of obesity. The investigators will also study if adenovirus infection can influence the outcome after surgery. In a subgroup of patients, hormonal changes after gastric by-pass surgery will be assessed. Lipid and protein patterns will be assessed in plasma and tissues. Omental and subcutaneous fat as well as liver biopsies and whole blood are stored in a biobank. The same tissues will be collected from non-obese controls undergoing gallbladder surgery.

Conditions

Interventions

PROCEDURE

Gastric bypass or cholecystectomy

Sponsors & Collaborators

  • Danderyd Hospital

    collaborator OTHER

  • Ersta Hospital, Sweden

    collaborator OTHER

  • Karolinska University Hospital

    collaborator OTHER

  • Karolinska Institutet

    lead OTHER

Principal Investigators

  • Erik Näslund, Professor · Karolinska Institutet

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-02-28
Primary Completion
2020-02-29
Completion
2020-02-29

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01736384 on ClinicalTrials.gov