The Effect of Cold Exposure on Physiological Markers

NCT07504718 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2026-04-07

No results posted yet for this study

Summary

The goal of this observational study is to examine how different physiological markers change over a two-day period after long-duration whole-body cold-water immersion in healthy young men and women. Specifically, the study aims to address the following questions:

* How do kynurenine pathway metabolites change after cold exposure?
* How do stress markers change after cold exposure?
* How do cytokine levels change after cold exposure?
* How do white blood cells count and distribution change after cold exposure?

Conditions

  • Healthy Adult Participants

Interventions

OTHER

Cold water immerssion

This intervention consisted of intermittent whole-body immersion in 14 °C water. After 20 min of immersion, the subject exited from the bath and rested for 10 min by sitting in the room environment, and then the same procedure was repeated. The cold stress continued until 170 min in total (120 min maximum total immersion time).

Sponsors & Collaborators

  • Lithuanian Sports University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
36 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-05-13
Primary Completion
2018-05-06
Completion
2018-05-06

Countries

  • Lithuania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07504718 on ClinicalTrials.gov