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Knee Pain Ejiao Paste for Knee Osteoarthritis

NCT07504562 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-04-01

No results posted yet for this study

Summary

To explore the analgesic efficacy of Knee Pain Ejiao Paste in the treatment of knee osteoarthritis (Qi and Blood Deficiency Pattern) after 12 weeks, using an Ejiao-free clear paste as a parallel control and incorporating a synthetic external control.

Conditions

Interventions

DRUG

Knee Pain Ejiao Paste

By comparing Knee Pain Ejiao Paste with the base formula, Knee Pain Ejiao-free Clear Paste, this study minimizes confounding factors such as dosage form, administration method, and matrix components. This approach allows for a precise evaluation of the incremental therapeutic benefits contributed by the addition of Ejiao, thereby providing direct evidence for the medicinal value of Colla Corii Asini.

DRUG

Knee Pain Ejiao-free Clear Paste

Using an Ejiao-free clear paste as a parallel control.

Sponsors & Collaborators

  • Shanghai University of Traditional Chinese Medicine

    collaborator OTHER

  • Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine

    collaborator UNKNOWN

  • Center for Pharmacometrics, Shanghai University of Traditional Chinese Medicine

    collaborator UNKNOWN

  • Institute of Digestive Diseases, Shanghai University of Traditional Chinese Medicine

    collaborator UNKNOWN

  • DongE E Jiao Coporation Limited

    collaborator INDUSTRY

  • ShuGuang Hospital

    lead OTHER

Principal Investigators

  • Yuelong Cao, Ph.D · Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-31
Primary Completion
2027-03-31
Completion
2028-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07504562 on ClinicalTrials.gov