Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation
NCT07504497 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2026-03-31
Summary
compare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under general anesthesia.
Conditions
- FESS Operation
Interventions
- DRUG
-
dexmedetomidine Lidocaine Saline
At the end of the surgery , the endotracheal tube cuff will be deflated and the study drug will be administered intratracheally. Manual positive pressure ventilation will be applied for drug distribution, followed by cuff reinflation
Sponsors & Collaborators
-
Younes Ahmed Younes
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-04-15
- Primary Completion
- 2026-12-15
- Completion
- 2026-12-15
More Related Trials
-
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
NCT05657028 ·Status: UNKNOWN ·Phase: NA
-
The Effectiveness of Intracuff Dexmedetomidine in Preventing Postoperative Sore Throat Following Prone Surgery
NCT07202624 ·Status: COMPLETED ·Phase: PHASE2
-
Attenuation Of Hemodynamic Response To Laryngoscopy. Role Of Dexmedetomidine. A Dose Finding Study
NCT05909215 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
NCT05941767 ·Status: COMPLETED ·Phase: NA
-
To Evaluate Effect of Nebulized Dexmedetomedine Upon Blunting Autonomic Response of Laeyngoscopy and Intubation in Patients Undergoing Elective Intubation
NCT07480304 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sinus Surgery
NCT07213037 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
NCT07462195 ·Status: RECRUITING ·Phase: PHASE4
-
Dexmedetomidine Improves the Surgical Field and Postoperative Recovery of Nasal Endoscopic Surgery
NCT04276545 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation
NCT01289769 ·Status: COMPLETED ·Phase: PHASE2
-
Antitussive Effect of Single-dose Dexmedetomidine With Low-dose Remifentanil Infusion
NCT02208505 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine in Non-intubated VATS
NCT05863416 ·Status: RECRUITING ·Phase: PHASE4
-
Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS
NCT05604599 ·Status: COMPLETED ·Phase: PHASE4
-
The Feasibility of Dexmedetomidine for Awake Fiberoptic Nasal Intubation
NCT00815893 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery
NCT02464722 ·Status: UNKNOWN ·Phase: PHASE4
-
Nasal Dexmedetomidine Versus Systemic Infusion Dexmedetomidine in Reducing Intraoperative Opioid Consumption in Nasal Endoscopic Surgeries
NCT07012213 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Dexmedetomidine and Agitation After Nasal Surgery
NCT06867302 ·Status: RECRUITING ·Phase: NA
-
Effect of Dexmedetomidine After Thyroidectomy
NCT02412150 ·Status: COMPLETED ·Phase: NA
-
The Effect of Dexmedetomidine on the Emergence Agitation in Nasal Surgery
NCT01513772 ·Status: COMPLETED ·Phase: NA
-
Effect of Single-dose Dexmedetomidine on Airway Reflex in Adult With Oral Intubation After Thyroidectomy
NCT01774305 ·Status: COMPLETED ·Phase: PHASE4
-
Comparative Study Between the Effect of Dexmedetomidine ,Midazolam or Bupivacaine Packing During FESS on Surgical Field Visualization
NCT07013955 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE3
-
Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings
NCT07298525 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients
NCT07164326 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Role of Nebulized Dexmedetomidine in Blunting the Effects of Direct Laryngoscopy and Endotracheal Tube on Heart Rate and Blood Pressure.
NCT06103721 ·Status: RECRUITING ·Phase: PHASE4
-
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
NCT06573957 ·Status: COMPLETED ·Phase: NA
-
Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers
NCT04659642 ·Status: UNKNOWN ·Phase: EARLY_PHASE1