MedTrace Logo

Effect of the Combination of Nitrate and Caffeine on Critical Power In Trained Male Cyclists

NCT07501806 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2026-03-30

No results posted yet for this study

Summary

This study is investigating the independent and combined effects of acute dietary nitrate and caffeine supplementation on performance during a 3-minute all-out cycling test in trained male cyclists. In a randomized, double-blind, placebo-controlled, crossover design, participants will complete four experimental conditions: nitrate, caffeine, nitrate plus caffeine, and placebo. Primary outcomes include end power (EP) and work done above end power (WEP), surrogate measures of critical power and W'. The study aims to determine whether combined supplementation provides additive benefits for severe-intensity exercise performance.

Conditions

  • Exercise Performance of Fit Athletes
  • Exercise Performance
  • Cycling Performance

Interventions

DIETARY_SUPPLEMENT

Dietary Nitrate

Participants consume concentrated nitrate-rich beetroot juice providing approximately 8.2 mmol of nitrate 3 hours prior to exercise.

DIETARY_SUPPLEMENT

Caffeine

Participants consume caffeine at a dose of 5 mg/kg body mass in capsule form 60 minutes prior to exercise.

OTHER

Placebo

Participants consume a nitrate-depleted beetroot juice placebo approximately 2-3 hours prior to exercise and a placebo capsule (maltodextrin) approximately 60 minutes prior to exercise.

Sponsors & Collaborators

  • Lindenwood University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-17
Primary Completion
2021-11-11
Completion
2021-11-11

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07501806 on ClinicalTrials.gov