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Acute Nitrate Supplementation in Cyclists

NCT01384968 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2012-10-17

No results posted yet for this study

Summary

Six days of dietary nitrate (NO3-) supplementation in the form of beetroot juice (\~0.5 L•d-1; 5.1-11.2 mmol NO3- •d-1) has been purported to reduce pulmonary oxygen uptake (VO2) during submaximal exercise and increase tolerance to high-intensity workloads. These results suggest that dietary nitrate supplementation has the potential to act as an ergogenic aid. Recently, we assessed submaximal oxygen uptake and 10 km time trial performance after 6 d of dietary nitrate supplementation in trained cyclists. We demonstrated an improvement in time trial performance compared to the nitrate-depleted placebo. However, the minimal dosage and duration of nitrate supplementation that is needed to elicit these performance effects remain largely unknown. Therefore, the purpose of the study is to assess performance capacity following an acute dose of nitrate supplementation consumed 3 h prior to the onset of exercise in trained cyclists. We will test the hypothesis that a single dose (140 mL; \~8 mmol NO3-) of dietary nitrate supplementation in the form of beetroot juice, ingested 3 h prior to exercise will improve time trial performance in trained cyclists compared to a nitrate-depleted placebo.

Conditions

  • Acute Nitrate Ingestion on Athletic Performance

Interventions

DIETARY_SUPPLEMENT

beetroot juice

170 mL beetroot juice (Beet It, James White drinks Ltd).

Sponsors & Collaborators

  • Maastricht University Medical Center

    lead OTHER

Principal Investigators

  • Luc van Loon, Ph.D. · Maastricht University

  • Naomi Cermak, Ph.D. · Maastricht University

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-07-31
Primary Completion
2012-01-31
Completion
2012-05-31

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01384968 on ClinicalTrials.gov