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The Acute Effects of Onnit Alpha Brain on Cognition and Mood States

NCT07495592 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-04-03

No results posted yet for this study

Summary

The purpose of this randomized, double-blind, placebo-controlled crossover study is to evaluate the efficacy of the acute effects of an investigational supplement (Alpha Brain or Alpha Brain 2.0) on improving cognitive performance, vigilance, and subjective mood in healthy adults compared to placebo during a period of acute sleep deprivation under conditions of controlled sleep deprivation.

Conditions

  • Cognitive
  • Mood and Cognitive Performance
  • Sleep Deprivation
  • Executive Function (Cognition)
  • Fatigue

Interventions

DIETARY_SUPPLEMENT

Alpha Brain proprietary cognitive dietary supplement

Alpha Brain is a proprietary investigational dietary supplement. The formulation contains a combination of dietary ingredients commonly used in cognitive supplement mixes.

DIETARY_SUPPLEMENT

Alpha Brain 2.0 proprietary cognitive dietary supplement

Alpha Brain 2.0 is a proprietary investigational dietary supplement. The formulation contains a combination of dietary ingredients commonly used in cognitive supplements and will be evaluated under double-blind conditions in a randomized, placebo-controlled crossover study.

DIETARY_SUPPLEMENT

Controlled Placebo

The placebo consists of an inactive placebo mix administered orally as two capsules.

Sponsors & Collaborators

  • Applied Science & Performance Institute

    lead INDUSTRY

Principal Investigators

  • Eric Sikorski, PhD · Applied Science and Performance Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-04-16
Primary Completion
2026-08-01
Completion
2026-08-15

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07495592 on ClinicalTrials.gov