Small Bowel Capsule Endoscopy in Lynch Syndrome
NCT07472686 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2026-03-16
Summary
The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown.
The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screening of small bowel (pre)neoplastic lesions between January 1st 2000 and December 31 2024.
Conditions
- MMR Mutation
- Small Bowel Adenoma
- Small-bowel Adenocarcinoma
- Lynch Syndrome
- Cancer
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-16
- Primary Completion
- 2026-06-30
- Completion
- 2026-12-31
Countries
- France
Study Locations
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