Weight Loss and Adipose Tissue Metabolism During Conservative Treatment of Obesity
NCT07456124 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22
Last updated 2026-03-06
Summary
This prospective observational study investigates weight loss and metabolic changes in adults with obesity undergoing standard clinical diet-induced lifestyle treatment and counseling. Participants follow a very-low-calorie diet followed by a conventional weight loss diet in addition to lifestyle counseling and are followed for 12 months. The study examines weight loss as the primary outcome and characterizes changes in body composition, fat distribution, glucose metabolism, inflammation, and adipose tissue biology as secondary outcomes.
Conditions
- Obesity & Overweight
- Obesity (Disorder)
Interventions
- BEHAVIORAL
-
Diet-Induced Weight Loss Program
Standard clinical obesity treatment consisting of a very-low-calorie diet for approximately 10 weeks followed by transition to a conventional weight loss diet with multidisciplinary clinical follow-up.
Sponsors & Collaborators
-
University of Helsinki
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-08-19
- Primary Completion
- 2016-08-17
- Completion
- 2016-08-17
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