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Short-Term Broccoli Supplementation and Acute Oxidative Stress Recovery

NCT07454265 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2026-03-06

No results posted yet for this study

Summary

The study aimed to evaluate the effects of short-term broccoli powder supplementation on metabolically demanding exercise performance, muscle power, and blood lactate recovery. It also investigated broccoli powder-derived sulforaphane bioavailability and its effects in attenuating exercise-induced oxidative stress. Seventeen healthy males (age 23.8 ± 4.9 years, height 182.3 ± 6.1 cm, weight 80.0 ± 12.8 kg), in a double-blind crossover design, three weeks apart, consumed ten standard doses of either broccoli powder or spinach powder as a placebo over a period of 2 weeks. They then performed a maximal progressive cycling task with concomitant analysis of expired gas composition. Plasma malondialdehyde (MDA) level was measured before and 60 min after the completion of the task, and blood lactate and muscle power (counter-movement vertical jump (CMJ) performance) were measured before and up to 60 min after exercise.

Conditions

  • Healthy Adult Male

Interventions

DIETARY_SUPPLEMENT

Broccoli powder

The intervention consisted of a single 35-mL scoop of broccoli powder (BrocAffex; 99.5% broccoli powder and 0.5% mustard seed powder), corresponding to 10 g of supplement and delivering 320 μg of glucoraphanin per serving. The supplement was mixed with 300 mL of chocolate oat milk (13 participants) or 300 mL of orange juice (4 participants).

DIETARY_SUPPLEMENT

Placebo (no broccoli-derived bioactives)

1/2 x 35 ml scoop of dried spinach powder blended with 300 ml of chocolate oat milk (13 participants) or orange juice (4 participants).

Sponsors & Collaborators

  • Lithuanian Sports University

    lead OTHER

Principal Investigators

  • Sigitas Kamandulis, Dr. · Lithuanian Sports University

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
37 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-11-30
Primary Completion
2025-01-01
Completion
2025-01-10

Countries

  • Lithuania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07454265 on ClinicalTrials.gov