MedTrace Logo

Sensory Substitution and Brain Plasticity Following Vision Loss

NCT07450677 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2026-03-05

No results posted yet for this study

Summary

The goal of this clinical investigation is to learn how the brain responds when visual information is converted into patterns of sound or touch in blind and sighted participants. The main questions it aims to answer are:

* Does converting visual information into sound or touch patterns change visual performance in the blind or blindfolded?
* How does the brain adapt to different kinds of sensory information?

Researchers will use brain imaging and simple performance tasks to see how people process and learn from this type of converted sensory input. The investigators will compare how individuals with and without long-term vision loss respond to these signals.

Participants will:

* Learn to use technologies to assist in visual information conversion into sound or touch patterns every day for 5 weeks;
* Visit the brain imaging center 3 times for brain scans and behavioral tests.

Conditions

Interventions

DEVICE

Electrotactile display (BrainPort)

The BrainPort is a non-surgical assistive device that translates digital information from a video camera to gentle electrotactile stimulation patterns on the surface of the tongue.

DEVICE

Vision-to-sound converter (AI Sight)

The AI Sight is an auditory technology software that can convert visual information into sound patterns, which can be delivered through regular headphones.

DEVICE

Sham

Participants will wear the assistive technology system, but there will be no active sensory signals applied.

Sponsors & Collaborators

Principal Investigators

  • Kevin C. Chan, PhD · Stanford University

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
8 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-01
Primary Completion
2030-08-31
Completion
2030-08-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07450677 on ClinicalTrials.gov