BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases

Summary

The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.

Conditions

• Glaucoma
• Macular Degeneration
• Glaucoma Suspect
• Optic Neuropathy
• Retinal Degeneration
• Visual Pathway Disorder

Interventions

DIAGNOSTIC_TEST

Visual Performance tests

Participants came to the clinic in person for 2 hours for visual performance tests once every 6 months for up to 5 years. These tests included virtual reality tests and tests on a computer screen to investigate performance during simulated daily life activities, such as driving, situations of low contrast and glare.

DEVICE

Brain-computer interface

The brain-computer interface (BCI) consists of a modified virtual reality goggle integrated with wireless no-prep electroencephalogram (EEG). The portable BCI is able to objectively measure multifocal steadystate visual evoked potentials in response to brain stimulation through presentation of visual stimuli in the goggle. The test is done in person and may take up to 30 minutes, once every 6 months for up to 5 years.

Sponsors & Collaborators

• National Eye Institute (NEI)

  collaborator NIH

• University of Miami

  lead OTHER

Principal Investigators

• Felipe A Medeiros, MD, PhD · University of Miami

• Henry Tseng, MD, PhD · Duke University

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-10-29

Primary Completion

2023-05-31

Completion

2023-05-31

Countries

• United States

Study Locations