Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalised Treatment, and Long-term Monitoring of Patients Across the Full Spectrum of Metabolic-associated Fatty Liver Disease (MAFLD).

Summary

The goal of this observational study is to create a detailed virtual model to better understand how Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) develops. This model will also help predict heart problem at different stage of the disease.

Conditions

• Metabolic Dysfunction-Associated Steatotic Liver Disease

Interventions

OTHER

Data recollection

Only data recollection for their use in the training, testing and early validation of computational models (but no other intervention) will be performed.

Sponsors & Collaborators

• Matical Innovation SL

  collaborator UNKNOWN

• Assistance Publique - Hôpitaux de Paris

  collaborator OTHER

• Jena University Hospital

  collaborator OTHER

• Institut National de Recherche en Informatique et Automatique

  collaborator UNKNOWN

• German Cancer Research Center

  collaborator OTHER

• MEDEX

  collaborator OTHER

• EUROPEAN LIVER PATIENTS ASSOCIATION

  collaborator UNKNOWN

• Betthera s.r.o.

  collaborator OTHER

• Bournemouth University

  collaborator OTHER

• University Hospital Heidelberg

  collaborator OTHER

• Fundacion Para La Investigacion Hospital La Fe

  collaborator OTHER

• University of Roma La Sapienza

  collaborator OTHER

• Charite University, Berlin, Germany

  collaborator OTHER

• Medical University of Vienna

  collaborator OTHER

• Saint-Luc University Hospital

  collaborator UNKNOWN

• University of Freiburg

  collaborator OTHER

• University of Leipzig

  collaborator OTHER

• Sheba Medical Center

  collaborator OTHER_GOV

• Imperial College London

  collaborator OTHER

• Hospital Universitari Vall d'Hebron Research Institute

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2026-02-23

Primary Completion

2026-06-02

Completion

2027-09-02

Countries

• Spain

Study Locations