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Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease

NCT04578301 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2022-05-18

No results posted yet for this study

Summary

Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.

Conditions

  • Liver Cirrhosis
  • Portal Hypertension
  • Surgery
  • Acute-On-Chronic Liver Failure
  • Non-Cirrhotic Portal Hypertension

Interventions

OTHER

No Intervention

No Intervention

Sponsors & Collaborators

  • University Hospital, Bonn

    lead OTHER

Principal Investigators

  • Michael Praktiknjo, MD · University Hospital, Bonn

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-22
Primary Completion
2025-12-31
Completion
2026-12-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04578301 on ClinicalTrials.gov