MedTrace Logo

Mechanical Insufflation-Exsufflation in Critically Ill Patients

NCT07420946 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-06-17

No results posted yet for this study

Summary

Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases. However, its use in critically ill ICU patients remains inconsistent and lacks standardized guidelines. Despite growing research, current practices vary widely in patient selection, treatment protocols, and safety management, with limited high-quality evidence to support clear recommendations. To address this gap, an international, multidisciplinary Delphi consensus study is needed to establish expert-based best practices and feasible guidelines for the safe and effective implementation of MI-E in the intensive care setting.

Conditions

  • Airway Clearance
  • Mechanical Insufflation-exsufflation
  • Mechanical Insufflation-exsufflation Session ( With Cough Assist)
  • Delphi Study
  • Consensus
  • Critical Illness
  • Critical Care
  • Critical Care, Intensive Care

Interventions

OTHER

Delphi Questionnaire

Statements on MI-E topics, rated along their level of appropriateness on a scale from 1 to 5. Multiple rounds are organised to reach consensus on a topic.

Sponsors & Collaborators

  • International Association of Non Invasive Ventilation

    collaborator UNKNOWN

  • International Academy of Non Invasive Ventilation

    collaborator UNKNOWN

  • International College of Experts of Non Invasive Ventilation

    collaborator UNKNOWN

  • Medipol University

    lead OTHER

Principal Investigators

  • Berkan Basançelebi · Medipol University

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-10
Primary Completion
2026-09-01
Completion
2026-12-01

Countries

  • Italy
  • Spain
  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07420946 on ClinicalTrials.gov