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Evaluation of Mechanical Power and Ventilator Parameters to Predict Weaning Success in the Intensive Care Unit

NCT07268989 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2026-05-18

No results posted yet for this study

Summary

The goal of this prospective observational study is to evaluate whether ventilator-based respiratory parameters can predict weaning success in adult intensive care unit (ICU) patients who are mechanically ventilated. The main questions it aims to answer are:

Can the mechanical power (MP) value predict successful extubation? Do other respiratory parameters-airway occlusion pressure (P0.1), negative inspiratory force (NIF), and the rapid shallow breathing index (RSBI)-provide additional prognostic value for weaning outcomes?

Participants will:

* Be adult ICU patients planned for weaning from mechanical ventilation.
* Undergo bedside ventilatory assessment within 2 hours after meeting clinical weaning criteria.
* Have the following respiratory parameters measured: MP, P0.1, NIF, and RSBI.
* Be monitored for 48 hours after extubation to assess weaning success (defined as no need for reintubation after extubation)

Conditions

  • Weaning Mechanical Ventilation
  • Mechanical Power
  • Negative Inspiratory Force
  • Airway Occlusion Pressure

Interventions

DIAGNOSTIC_TEST

Mechanical power

Non-invasive bedside evaluation of respiratory load, neural drive, and inspiratory muscle capacity using mechanical power (MP), airway occlusion pressure (P0.1), negative inspiratory force (NIF), and the rapid shallow breathing index (RSBI). • Measurements will be performed once within 2 hours prior to the extubation decision as part of routine ICU respiratory monitoring.

Sponsors & Collaborators

  • Anıl Berkay Balıtatlı

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2026-04-07
Completion
2026-04-07

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07268989 on ClinicalTrials.gov