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Antibacterial Effect of Two Different Intracanal Medicaments and Their Effect on Post-operative Pain

NCT07388888 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-02-05

No results posted yet for this study

Summary

Evaluation of antibacterial effect of two different intracanal medicaments on bacterial load in infected mature permanent teeth and their effect on post-operative pain level.

Conditions

  • Pulp Necrosis

Interventions

DRUG

Calcium Hydroxide (Ca(OH)2)

Non setting calcium hydroxide intracanal medicament is injected through the root canal for two weeks

DRUG

chitosan nanoparticles gel

Nano chitosan gel is injected through the root canal as an intracanal medicament for two weeks

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-28
Primary Completion
2027-02-28
Completion
2027-04-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07388888 on ClinicalTrials.gov