Effect of Different Products to Support Plaque Control During Daytime

Summary

The goal of this clinical trial is to test if the additional use of different commercially available products for a better breath and plaque reduction, taken during daytime between morning and evening tooth brushing, can reduce the plaque formation of participants during the day.

The tested products were:

* Listerine Total Care mouth rinse without alcohol.
* Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol.
* Colgate total advanced pro-shield mouth rinse without alcohol.
* Listerine Go Tabs.
* Wrigley Extra White Soft Chew Peppermint chewing gum.

The main questions it aims to answer are:

Can the tested product lower the plaque formation? Can the tested product improve the mouth freshness and breath?

Researchers will compare the tested products to not using any product (controls).

Participants need to come for a screening appointment and sign a consent form at first. If they are eligible, they need to come 6 times to the clinic. On each day, they need to come twice (morning appointment at 8 a.m. and evening appointment at 4 p.m.).

In the morning, they will have teeth cleaning and recieve one of the tested products to use on that day only (after tea break and lunch break), or they will recieve no product (control day).

In the evening, participant's teeth will be stained and oral photos will be taken. They will be asked about their perciption of freshness and good breath after using the product.

Conditions

• Dental Plaque
• Dental Plaque Accumulation
• Mouthwashes
• Chewing Gum

Interventions

DRUG

Oral B Pro-Health Multi-Protection Mouth Rinse refreshing mint without alcohol (0.07% CPC)

Participants need to use the mouth wash twice a day (after tea break and after lunch break) according to manifacturer instructions: vigorously swish 20mL of rinse in your mouth for 30 seconds and then spit out. Do not swallow. Do not dilute. They were dispensed in their original bottles. Participants were given a marked cup to measure the amount of MW.

DRUG

Listerine Total Care mouth rinse without alcohol

Participants need to use the mouth wash twice a day (after tea break and after lunch break) according to manifacturer instructions: vigorously swish 20mL of rinse in your mouth for 30 seconds and then spit out. Do not swallow. Do not dilute. They were dispensed in their original bottles. Participants were given a marked cup to measure the amount of MW.

DRUG

Colgate total advanced pro-shield mouth rinse without alcohol (0.075% CPC)

Participants need to use the mouth wash twice a day (after tea break and after lunch break) according to manifacturer instructions: vigorously swish 20mL of rinse in your mouth for 30 seconds and then spit out. Do not swallow. Do not dilute. They were dispensed in their original bottles. Participants were given a marked cup to measure the amount of MW.

DRUG

Listerine Go Tabs

Participants need to use the tablet twice a day (after tea break and after lunch break) according to manifacturer instructions: chew for 10 seconds to activate, swish around the teeth for 30 seconds to clean then swallow.

DRUG

Wrigley Extra White Soft Chew Peppermint chewing gum.

Participants need to use the chewing gum twice a day (after tea break and after lunch break) for 10 minutes duration.

Sponsors & Collaborators

• The University of Sydney, Sydney, Australia

  collaborator UNKNOWN

• King Abdullah University Hospital

  lead OTHER

Principal Investigators

• Axel Spahr · University of Sydney

• Lana Bader, DClinDent Perio · Jordan University of Science and Technology

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2020-09-18

Primary Completion

2022-05-16

Completion

2022-05-16

Countries

• Australia

Study Locations