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Visual Influences on Vestibular Adaptation

NCT07380256 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-04-17

No results posted yet for this study

Summary

The goal of this study is to learn whether a balance-training exercise called incremental vestibulo-ocular reflex adaptation (IVA) is safe and effective for adults with vision impairments, with or without additional vestibular (inner-ear balance) problems.

The main questions it aims to answer are:

* Does IVA cause only mild, temporary symptoms and no serious adverse events?
* Does IVA improve eye-movement reflexes, balance, and walking, and do these improvements differ between people with vision problems alone and those with both vision and vestibular impairments?

Researchers will compare adults with vision impairment only to adults who have both vision and vestibular impairments to see whether the groups respond differently to IVA.

Participants will:

* Complete symptom ratings before and after IVA
* Undergo tests of vestibular reflexes (e.g., VOR gain)
* Complete balance and walking assessments

Conditions

  • Vestibular Hypofunction
  • Binocular Vision Abnormalities
  • Reduced Vision

Interventions

DEVICE

StableEyes: Incremental Vestibulo-Ocular Reflex Adaptation (IVA)

IVA is delivered using the StableEyes device, which includes a lightweight head-mounted unit with inertial sensors and a micromirror that controls the position of a low-power laser target projected onto a wall. The device adjusts the target's movement based on the participant's head velocity to create a controlled visual error signal that induces vestibulo-ocular reflex (VOR) adaptation. During each session, participants sit about one meter from a blank wall and perform rapid, self-generated head impulses while visually tracking the moving laser target. The target appears at neutral, moves at a fraction of head velocity during each impulse, and briefly disappears before reappearing at center. Each session lasts 15 minutes and includes roughly 150 head impulses in the horizontal or vertical plane. The procedure has been well-tolerated in prior studies with no reported adverse events.

Sponsors & Collaborators

  • Emory University

    lead OTHER

Principal Investigators

  • Colin Grove, PT, DPT, PhD · Emory University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-04
Primary Completion
2029-12-31
Completion
2029-12-31
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07380256 on ClinicalTrials.gov