Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft

Summary

Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant. The aim of this study is to evaluate clinically and radiographically the efficacy of injectable bone graft versus ozonated olive oil gel to promote bone formation and improve outcomes in immediate implant cases. 16 immediate implants will be placed in mandibular premolar region the study will be devided equally and randomlly into two groups , Group 1: it will be 8 immediate implants represent the control group were the implants will be placed with injectable bone graft , Group 2: will be 8 immediate implant represent the study group were the implants will be placed with ozonated olive oil gel be used as a graft material . The implant stability will be assessed clinically using Ostell , and the bone density will be assed radiographically .

Conditions

• Dental
• Implant Osseointegration
• Ozone Therapy
• Bone Graft

Interventions

PROCEDURE

Immediate implant placement

Placement of a dental implant immediately after tooth extraction in the mandibular premolar region following standard surgical protocol.

BIOLOGICAL

β-tricalcium phosphate Injectable Bone Graft

Immediate implant placement in the mandibular premolar region with application of injectable bone graft material to the peri-implant defect.

BIOLOGICAL

Ozonated olive oil gel

Immediate implant placement in the mandibular premolar region with application of ozonated olive oil gel to the peri-implant defect.

Sponsors & Collaborators

• Suez Canal University

  lead OTHER

Principal Investigators

• Mohamed Said Hamed, Professor · Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry - Suez Canal University

• Shimaa Abdallah Metawea, B.D.S · Dentist at Ministry of Health and Population

• Ahmed Mohamed El Rawdy, Professor · Professor of Oral and Maxillofacial Radiology, Faculty of Dentistry - Suez Canal University

• Ahmed Abd elmohsen Younis, Assistant. Professor · Assistant. Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry - Suez Canal University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

20 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-12-10

Primary Completion

2025-05-10

Completion

2025-09-10

Countries

• Egypt

Study Locations