Eye Movement Parameters and Cognitive Functions in Older Adults
NCT07358598 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 210
Last updated 2026-01-23
Summary
Dementia most commonly occurs in elderly individuals, but currently there is still a lack of objective measurement methods that can detect cognitive impairment in older adults at an early stage. Eye movement is considered a clinical indicator with potential for screening mild cognitive dysfunction, and eye movement signals can be extracted to objectively evaluate cognition. Eye tracking has been used mostly to evaluate patients with neurodegenerative diseases such as Parkinson's disease. However, less attention has been paid to the relationship between eye movement and cognitive function in elderly individuals, as well as the association between eye movement data and abnormal cognitive subdomains. This cross-sectional study will recruit 0204 elderly individuals over the age of 65, divided into three groups (healthy group/mild cognitive impairment group/dementia group) according to the purpose of this study. Participants who have not been diagnosed with neurological diseases (such as Parkinson's disease or stroke), or have mental illness or visual impairments will be excluded. This study hopes to provide empirical data on eye movement signals and cognitive function in healthy older individuals, as well as to serve as a preliminary study for future development of eye activity stimulation to improve cognitive function in older adults.
Conditions
- Cognitive Dysfunction
Sponsors & Collaborators
-
National Sun Yat-sen University
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-01-17
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Taiwan
Study Locations
More Related Trials
-
Oculomotor Testing in the Differential Diagnosis of Dementia
NCT01577394 ·Status: COMPLETED ·Phase: PHASE3
-
Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease
NCT06924359 ·Status: RECRUITING
-
Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study
NCT06355830 ·Status: RECRUITING
-
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
NCT06737627 ·Status: RECRUITING
-
Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers
NCT04794634 ·Status: COMPLETED ·Phase: NA
-
Novel Retinal Imaging Biomarkers in Early Alzheimer's Disease
NCT01937221 ·Status: COMPLETED
-
Detecting Dementia in the Retina Using Optical Coherence Tomography
NCT03631069 ·Status: UNKNOWN
-
Study of the Correlation Between Macular Thickness Analyzed by Optical Coherence Tomography and the Visual Functions in Retinitis Pigmemtosa
NCT00784901 ·Status: COMPLETED
-
Natural History Study of Inherited Retinal Diseases
NCT07085533 ·Status: RECRUITING
-
Study of Dark Adaptation in Age-Related Macular Degeneration
NCT01352975 ·Status: ACTIVE_NOT_RECRUITING
-
Clinical Evaluation of VeriSee AMD in Screening for Age-Related Macular Degeneration
NCT05593913 ·Status: COMPLETED
-
Dynamic Light Scattering Ocular Measurement in the Detection of Dementia
NCT06613971 ·Status: RECRUITING
-
Comparison of OCTA Factors in Patients With or Without Amyloid Pathology: A Prospective Study
NCT05475158 ·Status: COMPLETED
-
Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults
NCT06836440 ·Status: RECRUITING ·Phase: NA
-
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?
NCT04276610 ·Status: TERMINATED ·Phase: NA
-
Evaluation of Visual Training System in Patients With Glaucoma
NCT06433102 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration
NCT02941263 ·Status: COMPLETED
-
The Relationship Between Macular OCTA and GCIPL and Their Combinational Index Using AI
NCT03369886 ·Status: UNKNOWN ·Phase: NA
-
Real-world of AI in Diagnosing Retinal Diseases
NCT05981950 ·Status: RECRUITING
-
Retinal Neurodegenerative Signs in Alzheimer's Diseases
NCT01555827 ·Status: COMPLETED ·Phase: NA
-
Retinal Imaging in Neurodegenerative Disease
NCT03233646 ·Status: RECRUITING
-
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
NCT04389437 ·Status: RECRUITING ·Phase: NA
-
The Aging Eye Cohort Study
NCT05851287 ·Status: RECRUITING
-
Patients Seeking a Visual Impairment Certificate
NCT06900855 ·Status: NOT_YET_RECRUITING
-
Impact of Age-related Macular Degeneration on Daily Living Activitie
NCT06333873 ·Status: NOT_YET_RECRUITING ·Phase: NA